The usefulness of the basophil activation test in monitoring specific immunotherapy with house dust mite allergens

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The usefulness of the basophil activation test in monitoring specific immunotherapy with house dust mite allergens

Introduction In clinical practice, reliable tools for monitoring specific immunotherapy (SIT) are of utmost importance. Aim To assess the usefulness of the basophil activation test (BAT) in monitoring SIT in paediatric patients with allergy to house dust mites (HDM). Material and methods Thirty-one children qualified for SIT with HDM, of whom 21 completed the SIT during the observation peri...

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[Specific immunotherapy with house dust mite allergens in an adult with severe atopic dermatitis].

Atopic dermatitis is a multifactorial chronic inflammatory disease whose unpredictable clinical course is influenced by a complex genetic basis (atopic diathesis) and multiple triggering factors. In adults, atopic dermatitis is characterized by severe pruritus, xerosis, lichenified plaques of eczema, and excoriation. No curative treatment is yet available. Specific immunotherapy with house dust...

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Usefulness of House Dust Mite Nasal Provocation Test in Asthma

PURPOSE We previously reported that the skin prick test was sensitive and the serum specific immunoglobulin E test was specific for predicting positive airway responses to house dust mites (HDMs) in patients with asthma. Because the nose and bronchus are one airway, the nasal provocation test would be more specific for predicting the bronchial responses to HDM than the skin test. METHODS The ...

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Changes in basophil activation during immunotherapy with house dust mite and mugwort in patients with allergic rhinitis

Background The basophil activation test (BAT) is a promising tool for monitoring allergen-specific immunotherapy responses. Objective We aimed to investigate the changes in basophil activation in response to the inhalant allergens of house dust mite (HDM) and mugwort pollen during immunotherapy in patients with allergic rhinitis. Methods We enrolled patients with allergic rhinitis who were ...

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Immunotherapy of house dust mite allergy

House dust mite (HDM) is a predominant source of indoor aeroallergen worldwide, which induces allergic diseases including allergic rhinoconjunctivitis, allergic asthma, atopic eczema and other allergic skin diseases. Allergen specific immunotherapy (AIT) is the only potential disease-modifying treatment of HDM allergic subjects. However, AIT remains underused due to no universally accepted alle...

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ژورنال

عنوان ژورنال: Advances in Dermatology and Allergology

سال: 2018

ISSN: 1642-395X

DOI: 10.5114/ada.2018.73169